There's a lot of skeletons in my closet, but I know what they're wearing. I'm not gonna act all ashamed of it.

I always love being in the company of women. It's all about good conversation and great wine.

The thing that I love about acting is the fact that I can help people feel things, know themselves or feel less alone. It's my form of expression, in the same way that someone might paint a picture or sing a song in that you're hoping that it moves somebody outside of their own way of thinking.

That's one of the lucky things about getting the success later on. I know how I want to dress, I know what kind of house I want to live in, I just know more about myself, and that's true about the roles I want to play and what parts of myself I want to express. You're just more in touch with yourself.

Since I had children I have taken huge amounts of time off. In a way it's a really good thing, in this show business especially, to have lots of private time, having lots of time to be in the world to observe people and read and take care of my kids helps me to come back into work with a thrill.

Never say never - and I certainly don't judge anyone who does it. But most of the characters I play are going through some kind of emotional turmoil, so my job requires me to have expression. If my face was froze, what right do I have to play that part? All the women who haven't done anything to their faces are still able to play great roles. And some of the ones who have done something have messed it up - they look freakish. Anyway, for me it's about playing women with rich lives - and the longer the life, the deeper the wrinkles.

In your 20s - and these are generalizations of course - I feel like I didn't care about as many things or as many people, or even myself, as much. There's more recklessness and more ruthlessness; you're not as considerate of how things land with other people I think.

At seventeen most people get their ears pierced or get a tattoo or something slightly taboo. That is what I love about Rodrigo Garcia, he's not conventional. He's someone who sees people in extraordinary ways, and forgives them for being such.

Sometimes they come to you and it's a small role, so it's about the experience and the journey and mixing with people you know you will learn from. Or sometimes it's a scene in a movie that you think, 'I just have to play this person.'

I got knockback after knockback at auditions. Just before ‘Mulholland Dr.’ my agent told me I was so intense I was freaking people out. She told me I was a brilliant actor but the feedback was that I made people feel uncomfortable because I was so nervous and intense. I just sat there and blubbed. My mum was staying in LA at the time and I went to her and said: ‘I just can’t do this. I’m not cut out for it.’ She just said: ‘Don’t believe a word people say about you. Forget them.’

Whatever is said about roles drying up, I intend to keep working. Certainly now the roles couldn't be more interesting - playing mothers, divorcees. I think it's going to be exciting to play a mother of teenagers. The longer your life, the deeper it gets.

It's unusual to spend even three full hours away from my newborn baby, it's like a piece of my body is back in the hotel room, and it does feel strange. But I love my work, though, it's not just a job for me, punching in my time card. I've always loved what I do, it's what makes me happy and I figure if I'm happy I'll be a good Mum too.

We had met with Ben Stiller here in LA when I was shooting The Ring and he was doing Meet The Fockers and we have friends in common. But we didn't know each other well. He's fantastic and we really had a great time on this and we were both laughing at where we were at, this other couple, and how it was mirroring what we were going through as well. It was clever writing in that way.

I don't know that any woman could ever not think about that at some point - even making the choice not to do it and getting to the place of peace of choosing not to be a parent, there would have still been some struggle in between. I'm not a man but I don't think it would occupy their minds as much.

Directors are our teachers, and I'm always craving to work with a great director. They're pretty much the first thing that interests me about a project. Let's put it this way: It'll take me a lot longer to read a script if there's no director attached.

Sometimes you arrive late in the process of filming, which makes it a little scary because they've already got this well-established technique going on, and all of the relationships are comfy and cozy. You have to figure out how to fit in, which can always be a scary first day.

Who are we when we leave our families? Who do we become? What are we capable of? That's something that never leaves us. It begins at that point in your life when you leave the nest, and I don't think we stop wanting to explore that question.

I've always loved to dance and keep fit but more recently I feel like I cannot keep up any longer and my back starts to hurt. And I get angry and then I have to really learn to forgive myself and go: you know what, you're nearly twice the age of some of the people in this room, give yourself a break.

I've done a few remakes now, as you know. And my philosophy is, you see the original film once, and that's it. You have to do whatever you can to shut it out, because you don't want your performance to be tainted. You don't want to fall into the trap of comparisons, basically.

It is a huge amount of pressure playing someone like Valerie Plame-Wilson. First of all who she is and what she's done is wildly intimidating and impressive. It is just scary to take on that responsibility, and you want to honor her story, an incredible story that affected us all. She is often doing things that were confusing to me, like her sexual prowess. I think that she is in a lot of pain and she has been really badly wounded along the way. She doesn't hold men in the highest regard... not just men but people.

There was a time I was very much blaming the way I felt on L.A, that it was a vacuum of creativity, of humor or anything organic, and I was really angry at the place. But then today I feel completely different - I love L.A.!