Each one of us fulfills a piece of a larger puzzle.

Most people, if you live in a big city, you see some form of schizophrenia every day, and it's always in the form of someone homeless. 'Look at that guy - he's crazy. He looks dangerous.' Well, he's on the streets because of mental illness. He probably had a job and a home.

The Trevor Project provides crisis-intervention and suicide-prevention services to lesbian, gay, bisexual, transgender, and questioning teens and young adults. It's truly a lifeline to so many young people who just need someone to listen to them.

You can write your own history.

Unfortunately, with men's health, we don't talk about it enough, and prostate cancer gets lost in the conversation.

The States doesn't think much about Canada, but we're attached. We're like Siamese twins. We can't do things - you can't roll over in the American bed without waking up the Canadians. It matters.

I hope that dog lovers around the world will support the Cruelty Free International global campaign to end the use of dogs in outdated and cruel experiments.

At home in L.A., Sunday is lazy. It's the wife and me lying in bed with coffee, watching 'The Soup' or something funny on TiVo. The kid will occasionally join us. Eventually, breakfast is at a place down the street called Paty's. And we always have some kind of great dinner - my wife makes a great roast beef.

I'm still a kid. I stretched it out.

I did my first musical in 4th grade as Huck Finn. By 11th grade, I was starring in 'Godspell' and 'Pippin' and pretending to be Che in 'Evita' in my bedroom. Singing has always been a huge part of me.

I'm torn about late parenting. I believe people should spend their twenties living and having fun and not having any regrets later. I also think people in their thirties generally make better parents but so many of my friends are having trouble - myself included - as fathers get older.

We want all LGBTQ kids to grow up in a world where they feel safe and equal to their straight peers.

As I got older, I realized that my life experience, what I really had, was always going to be more valuable than what I pretended to have.

Mental illness is the last frontier. The gay thing is part of everyday life now on a show like 'Modern Family,' but mental illness is still full of stigma. Maybe it is time for that to change.

Will Truman will be on my epitaph, but as an actor, I have to challenge myself.

I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important.

In the future, things will truncate! No, in the age of Twitter, we can't be upset when words become shorter.

I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done.

I think I was very lucky that I didn't get well-known until my early thirties. If it had happened when I was younger, you might have seen me falling out of nightclubs. I think I conducted myself as a much better human being because I was already married when all that came along (I got married five months after I got the role as Will).

I'm not sure sometimes if it was because Will was gay or it was a sitcom. But that combination does make it hard to become the new lead on the 'Sopranos.'

I never felt cool growing up. I was a bit of an outsider, but I discovered theatre very early on, which got me through.

There was a time when history was written by a few people, the winners. Now, history is written by all of us all the time... That's the thing we keep telling our 14-year-olds, you know: anything you do right now, it's not going anywhere.

When you become a father, everything changes.

I started to realise that it wasn't for me. Perhaps I didn't have to give my Hamlet before I died, that the world might be an OK place without my Hamlet, in fact.

Will isn't a screaming queen - that's Jack's part. They needed someone to play the part for America. It's just not the same as Britain. To have a gay character as a lead is risky.

I have accomplished a lot, but it didn't happen overnight for me. I was 35 when I got the show, and had been working professionally for 15 years. It would be a lot weirder if I were in my early 20s and stumbled into it.

But I was ready for it and I knew I could do it. I've just turned 40, I have a son and I feel more settled and driven than ever. I think my 40s will be my most prolific time. It's a very rare life you get to lead as a sitcom guy.

That's an amazing feeling, to walk onstage, and you're not thinking about anything, you're not thinking about your lines or what you're supposed to do - your body, your brain knows, so there's freedom. There's not fear, there's not nerves.

My most romantic job: I was a manager at Baskin-Robbins.

I think there's a certain objectivity that comes from being Canadian. You're partly British and partly American; you have a good bird's-eye view of both countries. So much of the comedy that comes out of Canada is impersonation - it's less 'look at me' than it is 'look at me playing other people.'

My wife is a real camper; it's a nice way to bond.

When I read the script for Will & Grace in 1998, I knew I was the only guy for the part.

As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me.

If you're doing an hour-long show, you're working movie hours, doing a 12-15-hour day. We work three or four hours a day, and get every third or fourth week off to give the writers time to write. It's the cushiest job in Hollywood.

I had played many gay characters before, but they were finite - guest characters in TV shows or characters in plays.

Growing up, my father was a financial analyst for an oil company. He was just a regular dad. And when I would say, 'Hey, come see my play,' he'd say, 'Sure.' He'd see one, 'Oh, good play' - you know, very typical dad reaction.

I was raised on 'Get Smart' and 'All in the Family' and 'M.A.S.H.,' and certainly when 'Cheers' came along, that was a big one.

We didn't, with 'Will & Grace,' set out to change the gay world. We just set out to be funny.

I like playing a character every day. I like having something to go back to. I always enjoyed that with 'Will & Grace.' I like the camaraderie. I like having a crew that I know and I can work with every day.

Back when I was in theater school, trying to figure out what I was going to do with my life, 'Sweeney Todd' was a huge touchstone for me, my favorite musical for sure.

I always get a little uppity when I hear the phrase 'TV actor.' It's like saying you're a magazine reporter. I was in the theater for ten years before I ever had a TV audition.

There wasn't an episode of 'Will & Grace' that didn't begin with my voice saying, 'Will & Grace' is taped before a live studio audience.

'Perception' was a different show than 'Will & Grace'. 'Will & Grace' was obviously a different show than anything I'd done before.

I did 'The Commish' and an episode of 'Neon Rider,' and then I got the series called 'Street Justice,' which I ended up doing about 18 episodes of.

Certainly 'Lonesome Dove' would be way hard now, because, I mean, back then I wasn't married. I didn't have kids.

As much as I loved Pacino and De Niro and wanted to be a dramatic actor, I also grew up on sitcoms. I grew up on 'M*A*S*H' and 'All In The Family' and 'Cheers.' And then around this time - this would have been '95, '96 - I was so into 'Friends' and 'Mad About You,' the idea of being on a sitcom became a very real thing that I wanted.

Probably one of the most surreal moments of my career was acting in front of Notre Dame with a mime.

I love everybody at TNT, and they were totally behind 'Trust Me.' I totally loved that show. I feel like it should have had more life.

I know where TNT's sweet spot is, and when I read 'Perception,' I thought, 'This is a chance to play a fascinating, fun, challenging character but still within the realm of something that will sit very well with 'The Closer' and 'Major Crimes' and the other shows there.'

I love playing anyone that does stuff that I don't do.