Politics is profoundly nonlinear.

Most educated people are not set up to listen or change their minds about politics, however sensible they are in other fields.

We need organisations like Vote Leave to operate permanently to give a voice to those who otherwise won't be heard.

I've learned over the years that 'rational discussion' accomplishes almost nothing in politics, particularly with people better educated than average.

If we want leaders to make good decisions amid huge complexity, and learn how to build great teams, then we should send them to learn from people who've proved they can do it. Instead of long summer holidays, embed aspirant leaders with Larry Page or James Dyson so they can experience successful leadership.

While our ancestor chiefs at least had some intuitive feel for important variables like agriculture and cavalry our contemporary chiefs (and those in the media responsible for scrutiny of decisions) generally do not understand their equivalents, and are often less experienced in managing complex organisations than their predecessors.

Economics is clearly a vital area of prediction for people in politics.

MPs have no real knowledge of how to function other than via gimmick and briefings.

The work of mathematicians on 'pure' problems has often yielded ideas that have waited to be rediscovered by physicists. The work of Euclid, Apollonius and Archimedes on ellipses would be used centuries later by Kepler for his theory of planetary motion.

It is very very hard for humans to lift our eyes from today and to go out into the future and think about what could be done to bring the future back to the present. Like ants crawling around on the leaf, we political people only know our leaf.

Vote Leave argued during the referendum that a Leave victory should deliver the huge changes that the public wanted and the U.K. should make science and technology the focus of a profound process of national renewal.

The stock market is an exploitable market where being right means you get rich and you help the overall system error-correct which makes it harder to be right (the mechanism pushes prices close to random, they're not quite random but few can exploit the non-randomness).

The reason why Whitehall is full of people failing in predictable ways on an hourly basis is because, first, there is general system-wide failure and, second, everybody keeps their heads down focused on the particular and they ignore the system.

We should stop selecting leaders from a subset of Oxbridge egomaniacs with a humanities degree and a spell as spin doctor.

When comparing many things in life the difference between average and best is say 30% but some people are 50 times more effective than others.

Tory MPs largely do not care about these poorer people. They don't care about the NHS. And the public has kind of cottoned on to that.

CRISPR-enabled 'gene drives' enable us to make changes to the germ-line of organisms permanent such that changes spread through the entire wild population, including making species extinct on demand. Unlike nuclear weapons such technologies are not complex, expensive, and able to be kept secret for a long time.

MPs are so cowed by the institutions and the scale of official failure that they generally just muddle along tinkering and hope to stay a step ahead of the media.

Most claims you read about psychological manipulation are rubbish.

If you want to make big improvements in communication, my advice is - hire physicists, not communications people from normal companies and never believe what advertising companies tell you about 'data' unless you can independently verify it.

As I've said many times, Vote Leave could only win because the Establishment's OODA loops are broken - as the Brexit negotiations painfully demonstrate daily - and they are systematically bad at decisions, and this created just enough space for us to win.

Action requires focus and priorities and these inherently require compromises and pragmatism.

If you look back at history, most important PR and propaganda was invented by the Communist Party.

Physicists and mathematicians regularly invade other fields but other fields do not invade theirs so we can see which fields are hardest for very talented people.