"I started doing science when I was effectively 20, a graduate student of Salvador Luria at Indiana University. And that was - you know, it took me about two years, you know, being a graduate student with Luria deciding I wanted to find the structure of DNA; that is, DNA was going to be my objective."

"Great wealth could make an enormous difference over the next decade if they sensibly support the scientific elite. Just the elite. Because the elite makes most of the progress. You should worry about people who produce really novel inventions, not pedantic hacks."

"If you go into science, I think you better go in with a dream that maybe you, too, will get a Nobel Prize. It's not that I went in and I thought I was very bright and I was going to get one, but I'll confess, you know, I knew what it was."

"If someone's liver doesn't work, we blame it on the genes; if someone's brain doesn't work properly, we blame the school. It's actually more humane to think of the condition as genetic. For instance, you don't want to say that someone is born unpleasant, but sometimes that might be true."

"I was always very curious about what a scientist's life was like when I was young. Of course, when I was young, you didn't have very many opportunities to find out with no web, TV. I was very lucky: I was born in the city of Chicago and went to the University of Chicago where I actually saw things."

"I never could read science fiction. I was just uninterested in it. And you know, I don't like to read novels where the hero just goes beyond what I think could exist. And it doesn't interest me because I'm not learning anything about something I'll actually have to deal with."

"One could not be a successful scientist without realizing that, in contrast to the popular conception supported by newspapers and mothers of scientists, a goodly number of scientists are not only narrow-minded and dull, but also just stupid."

"Here at the Cold Spring Harbor Laboratory, we have genetically rearranged various viruses and bacteria as part of our medical research. In fact, we have been able to create entirely new types of DNA molecules by splicing together the genetic information from different organisms - recombinant DNA."

"I do think one success of Northern Europe, which the United States came from, was its willingness to accept innovation in business practices like Adam Smith and the whole Enlightenment. It essentially made the merchant class free instead of controlled by the king and aristocracy. That was essential."

"One-third of all female infertility is the result of blocked fallopian tubes. If fertilization could be done in the lab and then the fertilized egg implanted in the womb, it would get around that problem. Millions of women who cannot have children would suddenly be able to."

"I have a son, who is a... not an ordinary form of schizophrenia, but clearly, cannot take care of himself. And the great fear of then, of all parents is, when the parents die, who takes care of your child? And the answer is: they become homeless."

"On the other hand, the sun of Naples might be conducive to learning something about the biochemistry of the embryonic development of marine animals."

"You move forward through knowledge. You prevail through knowledge. I love the word 'prevail.' Prevail!"

"Biology has at least 50 more interesting years."

"I don't want to die until I see cancer cured."

"If you succeed with your first dream, it helps. You know, people trust you, possibly, for the second one. They give you a chance to play out your second one."

"There are many people of color who are very talented."

"I don't want 100 different cures of cancer. I want, you know, give me five. So if you had, you know, five medicines, you could do away with 90 percent of cancer. That's sort of my objective. I think we're going to do it."

"Science moves with the spirit of an adventure characterized both by youthful arrogance and by the belief that the truth, once found, would be simple as well as pretty."

"I've had strong opinions probably since I was born. It makes you unpopular, but what can you do?"

"DNA was my only gold rush. I regarded DNA as worth a gold rush."

"Our goal should be to understand our differences."

"I would only once have the opportunity to let my scientific career encompass a path from the double helix to the three billion steps of the human genome."

"I wish there would be more movies about scientists."