There have to be people who are vocal about the advancement of knowledge over faith.

Denzel Washington has a great sense of humor. He did all those 'Nutty Professor' movies.

I can't believe I am hosting the Oscars. It's an honor everyone else said no.

The quest for Tommy Lee Jones' laugh begins now.

I wrote on a show called Johnny Bravo when I was at Hanna-Barbera.

Chris Elliott could read the phonebook and he's funny.

Some of those more out-there jokes were written in the wee hours of the morning. Somehow, they remained funny the next day.

With any half-hour comedy, it kind of takes on its own life and finds itself.

The success of 'The Simpsons' really opened doors. It showed that if you were working in animation you didn't necessarily have to be working in kids' television.

The good thing about Broadway is that you don't have to worry about an airdate. It gets done when it gets done.

'American Dad' is, by its nature, much more political.

I'm big on the importance of science, particularly right now at this point in time when there's sort of a systematic rejection of science by a lot of people in America.

The worst thing to happen at the Oscars would be if nothing happened. You want something unscripted, something to riff on, something kinda out there.

I'm bad at golf.

You would not want me on your football team.

Believe it or not, I have about the same success rate as anyone else. Sometimes you hit, sometimes you miss.

Don’t go snackin’ if you been tobaccin’.

I'm wide open to getting married, but actors are not easy people to date. You end up sharing that person with this other mistress that is their career. I very much like the traditional courtship method of making a date. That's what they do in normal places, but Hollywood's not normal.

I think at times I read too much of my own press. I wish I was better at taking in how great my life is, but that's surprisingly elusive. I tend to be very hard on myself and insecure about failing no matter what happens.

I'll tell you what I think is not okay. Have you ever seen that show on MSNBC, 'Lockup?' It's a reality show that takes place inside a prison. Do the prisoners have to sign release forms? Or do they have to be on it whether they like it or not?

I spent my entire childhood in the same town, in Kent. I went to grade school there. There was a boarding school that my mother taught at, called - appropriately enough - Kent School, that I went to. Yeah, pretty much my entire childhood was spent in that town.

At one point, I was hell-bent on being a Disney animator, and sort of got over that in college and wanted to do my own stuff. You know, towards the end of college I had actually planned to go to the Boston Conservatory of Music for musical theater.

The way Disney characters move, they're very kind of slow and fluid and flowing; one pose kind of eases into the next. If you look at a show like 'The Simpsons' and subsequently a show like 'Family Guy' - the characters will jerk from pose to pose a lot, a bit more snappy. Which sort of goes along with the writing tone of the show.

There are people on staff who have made that point, that the upside to a second Bush term is that it makes 'American Dad' work better. To me, the price is too high. I would gladly give up the comedy to have a President Kerry. But you work with what you have.

I always thought it would be funny to have the Parents Television Council write an episode of 'Family Guy' and give them full creative control. Then see how good the episode is. That's something we've actually discussed in the writers' room. We haven't proposed it yet, but if somebody from the PTC reads this, it might be worth discussing.

Every year, the Friday before the new Saturday-morning shows would premiere, the networks would do this big preview special, and I was always glued to the TV. As horrible as they were, they were entertaining at the time. There was a lot of showmanship from the networks based around the new lineup.

I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time.

From a writing standpoint, maybe television is a little more satisfying because it's not all hinging on one thing. You can experiment, week to week, and you can be a little narrower in your scope one week, and then be a little broader the next week. But with film, everything can look the way you want it to look. You can really sculpt the final product. So from a directorial standpoint, film is more satisfying. But, they're both forms of media that I'd like to keep involvement in.

I don't gravitate toward any particular genre. I like to do things that interest me, regardless of genre. I've had a blast doing Cosmos, and I'm said that it's coming to an end. I would like to do something else like that.

[With R-rated movie] you're not dealing with the restrictions imposed by the FCC. They're self-imposed. In a way, that does make it harder. You actually have to think about it, as opposed to just taking for granted that you're not going to be able to do this.