John Cleese was my personal favorite because he played my husband for a whole season - and Minnie Driver. We almost had our own, like, show all living in a house together. And Gene Wilder was just so dear.

He is not like Ron Swanson at all because he's very emotional and vulnerable. He is all of the things that I guess Ron was really deep down. He's not a Libertarian, but he does like bacon and meat.

People get up and say, 'I didn't prepare a speech because I didn't think I would win.' Well, that's dumb.

Sean is so funny. One time he went to Ireland for two weeks with his mother, and Ireland is so beautiful, and he got back; we were like, 'How was it?' and he was like, 'Ugh I was so bored.'

We do jigsaw puzzles. Here's a pro tip: Listen to an audiobook while doing it.

In terms of the first Christmas when I met everybody, I went over to Nick's grandfather's house where they were having the big Christmas dinner, and they have this tradition of this thing called oyster stew.

I feel like Nick and I have the best relationship and the best marriage.

I've done three Broadway musicals and tons of concerts and all kinds of things, but nobody knows that except the people in New York.

I'll quit coffee. It won't be easy drinking my Bailey's straight, but I'll get used to it. It'll still be the best part of waking up.

Theater is great because you're able to tell a narrative arc without a break. I think it's more about the material and whether what we get offered is good.

The ratio of celebrity divorces is probably about the same as non-celebrity divorces; it's just that the non-celebrity divorces don't get a lot of public scrutiny, normally.

That's all you ever want - to do your job well enough that people on the other end are happy.

My favorite thing to do is just stay home with the dogs and read or watch movies and be together.

People find it confusing I'm in a band, even though music was my main thing before acting.

I typed up a long email with different band name ideas and sent it to Stephanie, and they all started with 'the'.

People who have theater or sketch-comedy backgrounds seem to be more, you know, our speed. Like Amy Poehler and Will Arnett - we double date.

I think of myself as a character actress, and Karen's just one of the characters I've gotten to play, but I feel like Karen takes on so much more weight because the show was on for eight seasons, and it was such a popular show. But you have to move on to telling another story in a different world.

There's sacrificing for your art, and then there's just being dumb.

Playing Karen was so satisfying that it almost cured my acting bug completely. Not that I had conquered the world of acting. It was just that I had something to prove to myself when I started Will & Grace. Now I feel like, okay, well, I've satisfied that.

I used to watch 'ER' a little bit when it was at its kind of apex.

In real life, there's nobody more out than Sean. It was just in the press that he didn't want to say one way or another. I think he just felt it was nobody's business, but I feel like he came to it in his own time.

I never had a burning desire to have children. But then I met Nick, and I thought, 'This is the only person I'd do this with.' So we tried, but I was a little long in the tooth for that sort of thing. But we didn't turn it into a soap opera. We tried for about a year or so, and it didn't happen and took that to mean it wasn't meant to be.

Nick has said he would divorce me if I got Botox.

Madonna was very cool. I thought she was really nice, really present, and she worked really, really hard... She didn't necessarily know our real names in real-life, because why should she? Who cares? Some of the cast were really offended, like, 'She doesn't even know my name!' I'm like, 'Who cares? Madonna's doing our show. It doesn't matter.'

I lived in Chicago in the early '80s and did a ton of theater, and then Nick lived there in the '90s and did a ton of theater. Then we both moved to L.A. and did a ton of television.

I always hear some couples can't work together, and I don't get that. We have the most fun when we're working together.

Woody Harrelson played a long-term love interest of Debra Messing's; I think it was for a whole season. They almost cast Nick in that part. They almost had given to him. But at the eleventh hour, Jim Burrows put in a call to Woody, and he said he would do it.

I've always been a late bloomer, so I never feel like, 'Oh, I'm gettin' older; I guess everything is gonna stop.' I'm the opposite: 'Oh, I'm just getting started.'

Karen was always such a lawless rebel: carrying a gun in her purse, flirting with 14-year-old boys. She's the worst. You know that horrible guy Milo Yiannopoulos? She has about as many redeeming qualities as he has.

We met in April of 2000, and we weren't really an official couple until June or July. His family has a fishing trip they go on every year in Minnesota, so he had invited me to go and meet his whole family. There was, like, no cell phone service at the time; people were using those giant cordless phones that looked like a brick.

Nick is 11 and a half years younger than I am, so his mom is only, like, 11 or 12 years older than me. I didn't call her Mrs. Offerman because that would be weird because we're, like, the same age, so I think I went straight to Cathy, but there's a mom element, and his parents are so great.

Why can't I ever play a nice, normal, salt-of-the-earth type? Is there something I should know? It's fun to play villains and character roles, of course - but I'm sure it's also fun to be a really big star and play the lead in everything, where all you have to do is show up and not blink.

I tend to let the chips fall where they may. I don't know if that's right or wrong.

I had been watching the Emmys since I was probably 5 years old. Those shows, when you're a kid, it all seems like such a big, big deal, and only special certain people would win one of these big things like a Tony or an Emmy or an Oscar.

Selling a band predicated on nothing is always an interesting proposition, and of course, the fact of the matter is that I really started out in music before I ever acted, and I've done a ton of singing.

There were some articles written about our marriage, mythologising it, making it into the greatest love story ever told.

We already do a couple numbers with chairs - chairs being a classic, Bob Fosse-ish, showbizzy prop, but the punk element is that it's just me and Stephanie and this funky band from Austin.

Karen is like RuPaul - she's a character. It never occurred to me until now, but she is!

Actors talking about themselves. Nothing better!

Nobody's ever kept their sitcom character going after the show's off the air.

We have a two-week rule. We're never apart for more two weeks. Just not being separated for Jurassic periods of time seems to help. And no children probably helps a lot.

We're both big Glen Campbell fans - it's one of the things that united us in eternal love.

I started 'Will & Grace' when I was 39, and Nick started 'Parks and Rec' when he was 39. And he's really on the same trajectory; it's all happening with the same timing. It's so funny to see it all happening again.

Isn't that sort of what happened with gay marriage? Right before gay marriage was legalized, everybody was just losing their minds and, like, the worst possible things were happening, and it was just all like it couldn't get any worse, and then it suddenly got a lot better.

During 'Will & Grace,' we had so many things we had to go to where you get all dolled up. It's like pulling teeth for me.

He proposed, in London, in 2002.

I secretly had this name 'Nancy and Beth' come into my mind, and I thought, 'Oh my God, that's such a funny, interesting, weird name for a band.'

All I know is Karen is besties with Donny and Melania.

People are always flabbergasted, like, 'You sing?'

Nobody knows I sing. Even though I've done Broadway musicals. I would only pick it over acting because it's such a pure form of emotional expression.