If everybody loves you, you must be doing something wrong. It means there's no button being pushed... The only way that everybody loves you is toward the end of your career.

The key to humor is often self-loathing or sarcasm. In a sense, that's how self-loathing is made palatable.

At Ellis Island, I mean, you didn't go there if you arrived in first class. It was only the poorest, the people in the worst shape.

My wife and I had been to the genetic counselor; my wife is not Jewish - she's the shiksha goddess type - and was negative for everything. But I was positive. I carried the gene for three genetic disorders, which, if she had been positive for, we would have passed down to the child.

Sean Penn has announced his retirement from acting about 72 times.

At least in America, the narrative is I'm a Cannes favorite. But, in fact, I've had my best experience in Venice, both with the audience and the jury.

There's virtually nothing made up in 'The Immigrant.' So much of the film came from somewhere in my family's past. All the details are from my own family.

Anyone who starts badmouthing Latino immigrants is not only a racist but ignorant. You need to refer them to what was written about the Irish, the Jews, the Italians, any group you want.

I live up Laurel Canyon, and if I want to walk with my son, I have to drive to the park, which is so insane to me.