On MySpace ... the whole demographic of the stand-up comedy fan has changed. It's like an indie band thing. People think they've discovered you.

Weight Watchers says nothing tastes better than thin feels. I can think of a thousand things that taste better than thin feels.

There's something that's really fun about the challenge of making the mundane funny, too, I think.

Not that I don't think irreverent humor and someone being filthy is funny, I just do what I do. Any comedian would admit throwing an f-bomb in there would help get a reaction. ... I'm not on a Puritanical pursuit, but when I would curse in a joke, I believe I'm not done writing it.

I think when I started doing stand-up, that's when I really tried to question everything in my belief system which is - I think a pretty important part of being a comedian is really questioning things.

It's good to be back in New York. I have lived here ten years. I'm originally from Indiana. I know what most of you are thinking: Indiana: Mafia. But the fact of the matter is where I grew up there was something very similar to the Mafia: 4-H.

I wouldn't say that comedy brought me away from it.I think that my idea of faith was another obligation in my life.

Some of my fear and anxieties surrounding faith, I think, provides some good comedy for my act.

I liked the idea that my character was not gonna be the typical dumb guy that I play, typically. I also loved the fact that it was dealing with kind of adult-extended adolescence, which I think is always interesting -- a bunch of people that don't wanna grow up.

It's kind of hard to articulate, but, like, this notion of mercy, forgiveness, was very appealing for me. It was very profound. And it had a deep impact, and I think it still does.

It really never came up, but I think that in present-day America, they're - you know, and I touched on it in the initial clip - is that we are in the middle of this culture war.

I think stand-up comedy is this - it's this kind of indulgence and narcissism.

I didn't think that it's something that would happen. I didn't think I would be in the position, emotionally or financially, to be able to do that. But I've been lucky [to have big family].

I left the Midwest thinking I didn't fit in. But when I got to New York, I realized how truly Midwestern I was.

There was [ in New York] - some of it was this perception of the Midwest that I realized in this multicultural city that - and I don't think it's as true as it was - but everyone was kind of like, what, are you Jewish? Are you Italian? What are you? You know, are you black? Are you da-da-da? Are you Puerto Rican? And so I ended up - my ethnic identity was Midwestern, was white bread. And so it informed a lot of my stand-up.

I think I have a lot of voices in my head and I guess my inner critic is a female.

I've been doing stand-up for so long, I think 19 years, that I love topics I can also expand on. Once I identify a topic like, say, seafood, which is a big one right now, it's like there are different kinds of tangents I can go on to build a larger chunk.

I don't think comedians make an active decision to be a certain "persona." Comedians write the way they're going to write.

I think it's important to control your opportunities, because in the entertainment world, it's not up to you. I'm not sitting here under this naïve belief that someone in Hollywood is going, "Gaffigan! What kind of a show can I build around him?" So you have to find things that can showcase your point of view.

I personally have no interest in being a star or a celebrity. I want my stand-up comedy and how I think as a comedian to be recognized and successful.

I think comedians get too much credit or too much criticism for the style of comedy they do, and they generally do the style of comedy that works for them. There's no kind of shrewd calculation going into the type of standup we all do. It's like David Cross is supposed to be doing the David Cross' type of standup.

I wish, in some ways, I was the type of comedian who could do something blistering and topical, but I'm the guy who gets stuck in the revolving door and thinks I should write about that.

There's something about being a parent that has, I think, made me a better comedian.

Most single guys I know think fatherhood is terrifying.