I wasn't very good at it, but I knew that I loved acting immediately.

Alan Moore's first choice to be the Comedian... was Burt Reynolds. But I never saw myself as Burt Reynolds; I saw myself as Edward Blake.

I'm learning a lot how to be good at what I do and also how lucky I am and take it all in and be grateful for all this late in life success I've been having and it's good to have people that have been around and successful for awhile and work with them and see how they behave and it's why they are who they are and why they're still successful.

My kind of success has come a little bit later in life. I'm not 20 any more and these people I've been working with have been successful and good at what they do for a long time.

Sometimes in TV, it can get really stale, especially if you're doing these 23-episode years. It's a lot of work, and to put your family through that, on a location, is not always the greatest thing in the world.

Working exterior nights in Vancouver, when it's raining and snowing, is a little daunting, when you haven't slept.

There were rumors I wasn't going to die. The whole cast was sitting around the table reading the script. I fell on the floor - I'm not kidding. I looked up at Katherine Heigl, and she was crying.

The only reason I went to college was to play basketball. I injured my knee and couldn't play.

I would bend over backward to be back on Grey's. Any day, I'll choose lying in bed with Katherine Heigl looking over me over getting thrown against walls by supernatural persons at 5 in the morning.

Puerto Rico is beautiful. I mean, I love it. But it's hard to film here. It's hard to film an action movie here where you're outside, and you're running around all day.

Shonda Rhimes, especially, saw something in me that no one had and then wrote to my strengths for 'Grey's Anatomy.' That's the job I think really opened up a whole new world for me.

Jon Hamm - I know him. I love him.

I'm easy to get along with - I'm not a diva.

I was almost ready to call it quits - sick of doing a job and then being back on the unemployment line and trying to make ends meet. But I loved acting and didn't know what else to do.

I can't say enough about Ireland. I can't. I'd move there.

Acting is a hard profession. More than anything, it takes fortitude.

A 12-year-old can watch 'Spiderman.' A 12-year-old cannot watch 'Watchmen.'

I just didn't want to get bored playing a character, and that's kind of the benefit of doing films; you've lived with a character for four or five months and that's it, and you walk away from that character and you feel like you told a story.

If you look at my resume, I've more often than not played a very solid, decent human being.

In a Western, you don't over-explain.

I have this weird allergy where metal can't touch my skin.

I go to Comic-Con every year, generally with some project of some sort.

In a Western, you talk more with your eyes and your actions than you do with big speeches. I love that.

Women are surprised to see me on the street - like they're seeing a ghost. There's a lot of crying involved.